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Apis Derma Skin Care Cream is a natural skin care product containing an extract from the hive of
the honey bee ( species Apis Mellifera ). There is anecdotal evidence from case reports that this
cream may relieve the symptoms of eczema and psoriasis, and produce a marked improvement in these
skin conditions with continued usage. To date there have been no controlled clinical trials
assessing the efficiency of this product. The aim of this pilot study was to assess the efficacy of
Apis Derma Skin Care Cream in the treatment of atopic eczema.
A randomised, double blind, placebo-controlled trial was carried out involving 16 children aged
between 3 - 11 years in the Wellington area who were known to suffer from eczema. Each child was
given either active Apis Derma Skin Care Cream or placebo ( containing the base cream ) and
instructed to apply to the affected area twice daily for a 4 week period. Efficacy was assessed by
a self-administered questionaire based on the Children's Dermatology Life Quality Index ( CDLQI ).
This was completed before treatment was commenced, and at the end of each week ( 5 assessments in
total ). An overall impression on the efficacy of treatment was also assessed by asking each
subject ( or parent ) whether they thought the treatment was effective ( yes / no ).
Participants receiving the active product reported that treatment was effective more often than
those receiving placebo ( 5/8 vs. 0/8, p<0.01, chi-square test ). There was a trend of symptom
scores to be lower in the active product group compared with placebo, however this was not
statistically significant.
The results from this preliminary study suggest that Apis Derma Skin Care Cream is beneficial in
the treatment of eczema. They also suggest that it would be worthwhile to undertake a more detailed
clinical study, which would involve a larger number of subjects and include objective as well as
subjective measures of efficacy. While awaiting the outcome of such studies, cautious support can
be given to the claims of the manufacturer that Apis Derma Skin Care Cream is effective in the
treatment of eczema.
References
1. Davidson, R. Natural Apis Mellifera Honey Bee Skin Care.
2. Lewis-Jones, MS. Finlay, AY. The Children's Dermatology Life Quality Index (CDLQI ) : Initial
validation and practical use. Br J Dermatol 1955 : 132 : 942 - 949.
Another trial by Otago University as a precursor to conducting medical trials, was conducted and
found no toxicity or toxic effects can be detected as a result of using the cream.
Initial field test carried by Davidson's have yielded positive results and resulted in the
launch of the product.
It is the continued use of the cream by sufferers that lends the greatest evidence to the
integrity of the product. There are no reported side effects.
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